Autism

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Theoharides drug interactions

Theoharides Autism, basis NeuroProtek in Autism Science Digest 2010

• Autism drug interactions

• Autism mast cells - BBA 2012

• Autism serum IL-6, TNF, luteolin - Transl Psych 9-2015

• Autism subtype brain allergy - Clin Therapeutics May 2013

• Autism, brain inflammation - J Neuroinflammation 2012

• Autism, high serum CRH, neurotensin, dog model - Transl Psych 2104

• Autism, hippocampus, molecular profiling - medRxiv Oct 2022

• Autism, mastocytosis - Intl J Immunopathol Pharmacol 2009

• Autism, NeuroProtek - Clin Therapeutics May 2013

• Autism, NeuroProtek - IJIP6 2012

• Autism, Perinatal stress - BMC Peds 9-2012

• Autism, serum NT

• Mast cells, IL-37 - Intl J Mol Sci 2019

• Molecular Profiling of the Hippocampus of Children with Autism Spectrum Disorder - Abstract - Europe PMC

• Neuroinflammation, seizures, autism - J Neuroinflamm 2011

• Neurotensin, autism - PNAS 2016

• Perinatal mast cells, coronavirus, autism - J Pers Med 2021

• Extracellular vesicles are increased in the serum of children with autism spectrum disorder

• Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders

• Extracellular Mitochondrial ATP, Suramin, and Autism?

• Children with autism spectrum disorders, who improved with a luteolin-containing dietary formulation, show reduced serum levels of TNF and IL-6

• Exosomes in Neurologic and Psychiatric Disorders

• Potential Etiologic Factors of Microbiome Disruption in Autism

• Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism

• Mold and Immunity

• Effects of Mycotoxinson Neuropsychiatric Symptoms and Immune Processes

• Dysregulated brain immunity and neurotrophin signaling in Rett syndrome and autism spectrum disorders

• Autism Drugs in Wealthy Nations

• Elevated serum neurotensin and CRH levels in children with autistic spectrum disorders...‍

• Extracellular Mitochondrial Components Secreted from Activated Live Mast Cells Act as “Innate Pathogens” and Contribute to Autism Pathogenesis‍

• The “missing link” in autoimmunity and autism: Extracellular mitochondrial components secreted from activated live mast cells‍

• Focal Brain Inflammation and Autism‍

• NeuroProtek - 2012‍

• Autism, Seizures, JNI 2012‍

• Autism, Allergies JADD‍

• Novel therapeutic targets for autism‍

• Mast cells as targets of corticotropin releasing factor and related peptides‍

• Critical role of mast cells in inflammatory diseases and the effect of acute stress‍

• Autism: an emerging ‘neuroimmune disorder’ in search of therapy‍

• Autism Spectrum Disorders and Mastocytosis‍

• Mercury induces inflammatory mediator release from human mast cells‍

• Mitochondrial DNA and anti-mitochondrial antibodies in serum of autistic children‍

• Neurotensin is increased in serum of young children with autistic disorder

• Autism, elevated serum CRH, NT-Transl Psych 2014

• Autism, NeuroProtek Clin Therapeutics May 2013

• Autism, NeuroProtek, IJIP6-2012

• Mast cells, stress, fear, autism, Intl J Mol Sci 2019

• Theoharides Autism, basis NeuroProtek in Autism Science Digest 2010

• Atopic conditions, Clin Therapeutics May 2013

• Autism subtype brain allergy Clin Therapeutics May 2013

• Autism, allergies, JADD 2011

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Autism Diagnosis & Treatment

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• Children with Autism Spectrum Disorders

Bladder Health

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• CystoProtek clinical Can J Urol

• Cystoprotek IJIP

• Genitourinary mast cells 2015

• Interstitial cystitis-bladder pain syndrome - J Family Practice 6-2011

• Intimate contact - Clin Ther 2019

Brain Allergy

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• Atopic conditions, Clin Therapeutics May 2013

• Autism subtype brain allergy Clin Therapeutics May 2013

• Autism, allergies, JADD 2011

Brain Fog

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• Brain Fog - Frontiers Neuroscience - July 2015

• Brain inflammation, Long-COVID - Cells 2023

• Luteolin, Long-COVID brain fog - Biofactors 2021

Brain Health

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• Stress Blood Brain Barrier‍

• Brain Inflammation‍

• Non-steroidal Drugs Inhibit SSRI Antidepressant Action‍

• Mast Cells - The Immune Gate to the Brain

Brain Inflammation

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• Atopic Diseases and Inflammation of the brain in the pathogenesis of autism spectrum disorders

• Autism, brain inflammation, J Neuroinflammation 2012

• Brain inflammation, Long-COVID, Cells 2023

• Brain mast cells chapter, Theoharides 2022

• Brain mast cells, Eur J Pharmacol July 2015

• Exosomes, brain, Clin Therap 2014

• Factors affecting neurodevelopment, J Reg Homeost Agents 2019

• FMS biomarkers, JPET 2016

• FMS, JPET 2015

• Gut Brain Axis and Neuroimmune disorder, Clin Therap May 2015

• Mast cells in meningiomas and brain inflammation 2016

• Mast cells, brain inflammation and autism, Eur J Pharmacol 2016

• Stress, inflammation, Clin Ther 2020

• Stress, inflammation, autoimmunity, Clin Ther May 2020

• Stress, mast cells, Annals Allergy, Asthma Immunol 2020

• Stress, MS Autoimmuni Rev 2013

• Stress, natural treatments, J Reg Hoemost Agents 2019

• The “missing link” in autoimmunity and autism, Autoimm Rev 2013

COVID-19 & Long COVID Syndrome

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• Calprotectin, inflammation, COVID-19 - 2022

• COVID-19, mast cells, luteolin highlights

• COVID-19, PAF, microthromboses - 2020

• COVID, mast cells, treatment - 2022

• Spike protein, mast cell, microgia, neuro-COVID Cells - 2023

• Spike proten stimulates mast cells via TLR4

• Spike, coronavirus, long-COVID - 2022

• Brain inflammation, Long-COVID - Cells 2023

• Luteolin, Long-COVID brain fog - Biofactors 2021

• COVID-19 and multisystem inflammatory syndrome

• COVID-19 brain inflammation and autism spectrum disorder

• COVID-19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin

• COVID-19, microthromboses, inflammation, and platelet activating factor

• Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue

• Luteolin supplements: All that glitters is not gold

• Potential association of mast cells with coronavirus disease 2019

• Be aware of SARS-CoV-2 spike protein: There is more than meets the eye

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Flavonoids Luteolin

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• New Evidence indicates that the flavonoid luteolin is a better inhibitor of mast cells than the drug cromolyn

• Luteolin inhibits spike protein of severe acute respiratory syndrome coronavirus

• Luteolin Isolated from Juncus acutus L., a Potential Remedy for Human Coronavirus 229E

• Luteolin is a potential inhibitor of COVID-19: An in silico analysis

• Covid-19, Mast Cells, Lueolin Highlights

• Luteolin - Neurotrauma 2020

• Mast Cell Activation Beyond Histamine And Tryptase - exp Rev Clin Immunol 2023

• Mast Cells, Microglia - neuro-covid cells 2023

• Sars-CoC-2 Spike Protein Mast Cells - ijms, 2023

• Sars-CoV-2 Spike Protein, Microglia - mol Neurobiol 2023

• Sars‐CoV‐2 Spike Protein And Paf - biofactors 2022

• Spike Protein, Mast Cell, Microgia, Neuro-covid cells 2023

• Spike, Coronavirus, Long-covid - mol Neurobiol-nature 2002

• Covid Treatment, Mast Cells - intl J Inf Dis 2022

• Kempuraj - luteolin 2020

• Luteolin supplements- All that glitters is not gold - Biofactors 2020

• Luteolin - Neuropsychiatric Disorders

• Luteolin, COVID-19, mast cells, cytokines - BioFactors 2020

• Luteolin, Long-COVID brain fog - Biofactors 2021

• Luteolin, MS - J Neuroinflamm 2009

• Luteolin, Post-Lyme - 2016

• Methlut lotion - Intl J Immunpath Pharm 2017

• Methoxyluteolin, mast cells - JACI 2015

• Methoxyluteolin, mast cells - mTOR, JPET 2017

• Autism, elevated serum CRH, NT-Transl Psych 2014

• Autism, NeuroProtek Clin Therapeutics May 2013

• Autism, NeuroProtek, IJIP6-2012

• Mast cells, stress, fear, autism, Intl J Mol Sci 2019

• Theoharides Autism, basis NeuroProtek in Autism Science Digest 2010

• CFS , flavones J Neuroinflamm 2014

• Mast cells, COVID-19_Annals Allergy Asthma 2021

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Mast Cells

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• Luteolin-rich fraction from Perilla frutescens seed meal inhibits spike glycoprotein S1 of SARS-CoV-2-induced NLRP3 inflammasome lung cell inflammation via regulation of JAK1/STAT3 pathway

• Luteolin Is More Potent than Cromolyn in Their Ability to Inhibit Mediator Release from Cultured Human Mast Cells

• Luteolin is a potential inhibitor of COVID-19

• Podcast: Mast Cell Matters: Deep dives on MCAS

• Mast Cell Over-Activation, and How it Affects our Mind and Body Well-Being
 (Passcode: q*bwPX3M)

• Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

• Mast cells, Pancreatitis_2014

• Mast cell activation and microbiome

• Mast cell activation beyond histamine and tryptase Exp-Rev-Clin-Immunol_2023

• Mast cell activation disorders, Exp Rev Clin Immunol 2014

• Mast cell mediator disorder, Exp Rev Clin Imminol 2019

• Mast cell, obesity asthma, Allergy 2014

• Mast cells and COVID-19_medRxiv_2022

• Mast cells and SARS-CoV-2_NEJM, 2023

• Mast cells in allergy inflamm Curr Pharm Des 2012

• Mast cells brain inflammation and autism Eur J Pharmacol 2016

• Mast cells, COVID-19_Annals Allergy Asthma 2021

• Mast cells, dendritic cells_JACI 2021

• Mast cells, fear, autism, Intl J Mol Sci 2019

• Mast cells, FMS, pain, Front Cell Neurosci 2019

• Mast cells, IBS, Dig Dis Sc 2014

• Mast cells, IL-1 beta, PNAS 9-2018

• Mast cells, IL-37, Intl J Mol Sci, 2019

• Mast cells, Immunity_IJMS 2023

• Mast cells, inflammation, BBA 2012

• Mast cells, mastocytosis and supplemental, NEJM July 9, 2015

• Mast cells, meningiomas_J Neuroinflam, 2015

• Mast cells, migraines_Brain Res Rev, 2005

• Mast cells, MS, strress, Autoimm Rev, 2013

• Mast cells, neuroinflammation_Front Cell Neurosc, 2019

• Mast cells, neuron contacts, Clin Ther 2016 main

• Mast cells, obesity, MI, Trends Pharm Sc 2011

• Mast cells, pancreatic cancer_NEJM, 2008

• Mast cells, stress, asthma Ann Allergy Asthma Immunol 2012

• Mast cells, stress, fear, autism, Intl J Mol Sci 2019

• Mast cells, stress, heart, Ann Allergy Asthma Immunol 2014

• Mastocytose - fatigue

• Mastocytosis, cognitive impairment 2012